Topics
Basics in Biological Rhythm Research
This part addresses
fundamentals in circadian rhythm research:
Entrainment, Phase-shift, Phase-response Curve, Aschoff's Rules,
Masking Effects. The Cellular Basis of Circadian Clocks, Genetic Basis
of the Circadian Clock as well as Data Analysis Techniques
Lectures by: Prof. L. Edmunds (SUNY New York), Dr. S. Gorbey (Uni
Heidelberg), Prof. B. Lemmer (Uni Heidelberg), Prof. S. Michel (Uni Leiden), Prof. J. Waterhouse (Uni
Liverpool)
Biological Rhythms in Different Species
The second introduction part is about:
Morphology and Histology of Biological Clocks. Rhythms in Arthropodes
and Plants. Circadian Oscillators and the Cell Cycle. Rhythms in
Signaltransduction and talks about Shift-work and Jet-Lag.
Lectures by: Prof. L. Edmunds (SUNY
New York), Prof. G. Fleissner (Uni Frankfurt), Dr. G. Fleissner (Uni
Frankfurt), Prof. B. Lemmer (Uni Heidelberg), Prof. A. Reinberg (CNRS,
Paris), Prof. E. Wagner (Uni Freiburg).
Chronomedicine and Chronopharmacology
The main part of the
lectures are related to the growing field of circadian rhythms in
diseases and Chronopharmacology:
Chronobiology and Chronopharmacology of the Endocrine and
Cardiovascular System. Sleep Apnea.
Chronoepidemiology, Chronopharmacokinetics and Drug Delivery. Treatment
of Hypertension, angina pectoris and Asthma. Chronopharmacology and
Chronotoxicology of Anticancer Drugs, as well as Rhythms in Thermoregulation and Sleep.
Lectures by: Prof. I. Ashkenazi (Uni Tel Aviv), Prof. J-L. Elghozi (Uni Paris), Prof. Ch. Focan (Liége), Dr. S. Gorbey (Uni Heidelberg), Prof. B. Lemmer (Uni Heidelberg), Prof. F. Lévi (INSERM, Villejuif); Prof. M. Middeke (Uni Muenchen), Dr. F. McInnes (Uni Strathclyde, Glasgow), Prof. R. Manfredini (Uni Ferrara), Prof. A. Reinberg (CNRS, Paris), Prof. Y. Touitou (Uni Paris VI), J. Schmitt (Theresienkrankenhaus Mannheim), Prof. M.H. Smolensky (Uni Houston, Texas).
Practical Approaches
There
will be also a part of "real live experiments":
Self-assessment of 24-hr heart rate and blood pressure rhythms (ABPM).
Self-assessment of 24-hr activity, temperature, peak flow or grip
strength, as well as a demonstration of our telemetric facility for rat
and mice and a visit of a Sleep Lab.
Demonstrations by: Dr. S .Gorbey (Uni Heidelberg), J. Schmitt
(Theresienkrankenhaus Mannheim).